...The production of sebum increases in line with the generation of certain hormones. During the menstrual cycle, the production of androgens in women increases at certain times. The activity of these androgens (e.g. testosterone) is believed to be responsible for acne, so if their production could be reduced, then the incidence of acne should be likewise reduced. Androgens promote acne by increasing the rate of production of oily sebum by the sebaceous glands in the skin. This gives some women a natural healthy glow, while others are provided with a sticky oil slick that mixes with dead skin cells to block up skin pores....»
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«...Oral antibiotics are used in the management of moderate- to-severe acne and acne-like disorders, such as rosacea. The tetracyclines are the usual drug of choice; of the tetracyclines, minocycline is considered the gold standard. Both the tetracyclines and the less frequently used erythromycin preparations inhibit the growth of Propionibacterium acnes, which decreases free fatty acid production and pustule formation....»
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